[1]QU Chuan-yong,QIN Qing-hua.Bone remodeling under multifield coupled loading[J].CAAI Transactions on Intelligent Systems,2007,2(3):52-58.
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Bone remodeling under multifield coupled loading

CAAI Transactions on Intelligent Systems[ISSN 1673-4785/CN 23-1538/TP] Volume: 2 Number of periods: 2007 3 Page number: 52-58 Column: 学术论文—人工智能基础 Public date: 2007-06-25
Title:
Bone remodeling under multifield coupled loading
Author(s):
QU Chuan-yong; QIN Qing-hua
School of Mechanical Engineering, Tianjin University, Tianjin 300072, C hina
Keywords:
bone remodeling;  multifield;  intelligent materials;  biomaterials
CLC:
R318.01，Q64
DOI:
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Abstract:
The bone remodeling process is investigated theoretically and experime ntally within the framework of extended adaptive elasticity. Coupling between in ternal and surface remodeling is considered to better simulate the bone remodeli ng process. The interactions of multifield loading, including transverse press u re, electrical fields, and magnetic fields, are taken into account when simulati ng bone remodeling. A semianalytical solution based on the statespace method w as used to analyze the remodeling process of inhomogeneous bone materials subjec ted to multifield loading. Numerical examples are presented to verify the prop o sed theoretical model for coupled internal and surface bone remodeling under mec hanical and electromagnetic loading. The results are in contrast to former work which did not consider coupling between internal and surface remodeling. The mag nitude of electrical field changes is found to be lower and the remodeling time is significantly shorter. This implies that the coupling between internal and su rface remodeling plays an important role in the bone remodeling process. On the other hand, the results show that environmental loading can change the structure and properties of bone tissues.
References:
［1］WOLFF J. Das Gesetz der Transformation der Knochen ［M］. Berlin: Hirschwald, 1892.
［2］COWIN S C, HEGEDUS D M. Bone remodeling I: Theory of adaptive elasticity ［J］. Journal of Elasticity, 1976（6）: 313-326.
［3］HEGEDUS D M, COWIN S C. Bone remodeling II: small strain adaptive elastici ty ［J］. Journal of Elasticity, 1976(6): 337-352.
［4］COWIN S C, NACHLINGER R R. Bone remodeling III: Uniqueness and sta bility i n adaptive elasticity theory ［J］. Journal of Elasticity, 1978,8: 285-295.
［5］GJELSVIK A. Bone remodeling and piezoelectricity—Ⅰ ［J］. Journal of Biom echanics, 1973(6): 69-77.
［6］GJELSVIK A. Bone remodeling and piezoelectricity—Ⅱ ［J］. Journal of Bi omechanics, 1973(6): 187-197.
［7］[JP3]MARTIN R B, BURR B B. A hypothetical mechanism for simulation of os teon al remodeling by fatigue damage ［J］. Journal of Biomechanics, 1982,15: 37-147 .
［8］BEAUPRE〖AKA^] G S, ORR T E, CARTER D R. An approach for timedependent bo ne model ing and remodeling: theoretical development ［J］. Journal of Orthopaedic Resear ch,1990(8):651-661.
［9］BEAUPRE〖AKA^〗 G S, ORR T E, CARTER D R. An approach for timedependent bone modeling and remodeling: application: a preliminary remodeling simulation ［J］. Journal of Orthopaedic Research, 1990，8: 662-670.
［10］BESSETT C A, VALDES M G, HERNANDEZ E. Modification of fractur e repair w ith selected pulsing electromagnetic fields ［J］. Journal of Bone and Joint Sur gery—American Volume, 1982，64: 888-895.
［11］MCLEOD K J, RUBIN C T. The effect of lowfrequency electrical field on os te ogenesis ［J］. Journal of Bone and Joint Surgery—American Volume, 1992，74: 92 0-929.
［12］GIORDANO N, BATTISTI E. Effect of electromagnetic fields on bone mineral de nsity and biochemical markers of bone turnover in osteoporosis: a singleblind, randomized pilot study ［J］. Current Therapeutic Research, 2001，62: 187-193. 
［13］KORENSTEIN R, SOMJEN D, FISCHLER H, et al. Capacitative pulsed electric s ti mulation of bone cells. Induction of cyclicAMP and DNA synthesis ［J］. Bioche m Biophys Acta, 1984,803:302-307.
［14］LUBEN R A, CAIN C D, CHEN M C Y, et al. Effects of electromagnetic stimul i on bone and bone cells in vitro: Inhibition of responses to parathyroid hormone by lowenergy lowfrequency fields ［J］. Proc Natl Acad Sci, 1982，79:4180- 4 184.
［15］FRIEDENBERG Z B, ZEMSKY L M, POLLIS R P, et al. The response of nontraum atized bone to direct current ［J］. J Bone Jt Surg, 1974,56A:1023-1030.
［16］LAVINE L S, LUSTRIN I， SHAMOS M H， et al. The influence of electric cu r rent on bone regeneration in vivo ［J］. Acta Orthop Scand, 1971,42:305-314. 
［17］BRIGHTON C T, FRIEDENBERG Z B, ZEMSKY L M， et al. Directcurrent sti mu lation of nonunion and congenital pseudarthrosis: Exploration of its clinical ap plication ［J］. J Bone Jt Surg, 1975，57A:368-377.
［18］SHARRARD W J, SUTELIFFE M L, ROBSON M J,et al. The treatment of fibrous n on union of fracture by pulsing electromagnetic stimulation ［J］. J Bone Jt Surg, 1982，64B:189-193.
［19］QIN Q H, YE J Q. Thermoelectroelastic solutions for internal bone remodel in g under axial and transverse loads ［J］. International Journal of Solids and St ructures, 2004，41: 2447-60.
［20］QIN Q H, QU C Y, YE J Q. Thermoelectroelastic solutions for surface bon e remodeling under axial and transverse loads ［J］. Biomaterials, 2005，26: 6798- 6810.
［21］QU C Y, QIN Q H. Evolution of bone structure under axial and transverse l oads ［J］. Structural Engineering and Mechanics, 2005, 24(1): 19-29.
［22］COWIN S C, VAN BUSKIRK W C. Internal bone remodeling induced by a medu llary pin ［J］. Journal of Biomechanics, 1978，11:269-75.
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