[1]ZHA Liu-sheng,LIU Zi-wei.Biomolecular recognition in responsive hydrogels and their use as intelligent drug delivery systems[J].CAAI Transactions on Intelligent Systems,2007,2(6):38-47.
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Biomolecular recognition in responsive hydrogels and  their use as intelligent drug delivery systems

CAAI Transactions on Intelligent Systems[ISSN 1673-4785/CN 23-1538/TP] Volume: 2 Number of periods: 2007 6 Page number: 38-47 Column: 学术论文—智能系统 Public date: 2007-12-25
Title:
Biomolecular recognition in responsive hydrogels and  their use as intelligent drug delivery systems
Author(s):
ZHA Liu-sheng1; 2;  LIU Zi-wei1
1.State Key Laboratory for Modification of Chemical Fibers and Polym er Materials，Donghua University, Shanghai 201620, China;
 2.Research Center for Analysis and Measurement, Donghua University, Shanghai 201620, China
Keywords:
intelligent hydrogels;  biomolecular recognition;  intelligent drug delivery syste m;  stimulative response
CLC:
Q811
DOI:
-
Abstract:
Biomolecule recognition responsive hydrogels are the intelligent polymer materia ls which can recognize specific biomolecules and respond to them mimicking the m oleculerecognizing process of life activity. The intelligent systems fabricate d from the hydrogels resemble the biological systems with feedback and equilibriu m functions, and they have a great deal of potential applications in the fields of bioengineering and biomedicine. In this paper, we give a deta iled overview of current research in the preparation of intelligent hydrogels th at respond to specific molecules, such as glucose, enzymes, antigens, nucleic ac id, etc. The application of these hydrogels in intelligent drug delivery system s is also introduced. Then the paper explains the relationship between the struc tures and functions of biomolecular recognition in responsive hydrogels, giving a good basis for the development of new types of intelligent drug delivery syste ms.
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